L-Malic Acid

Basic information

Product Name:L-Malic Acid
CasNo.:97-67-6
MF:C₄H₆O₅
MW:134.089

Physical and Chemical Properties

Purity:99%
Boiling Point:101-103 °C(lit.)
Packing:clear colourless solution
Throughput:

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Product Details

CasNo： 97-67-6

MF： C₄H₆O₅

Appearance： clear colourless solution

High quality purity >99% L-Malic Acid 97-67-6 for sale

Molecular Formula:C4H6O5
Molecular Weight:134.089
Appearance/Colour:clear colourless solution
Vapor Pressure:7.19E-05mmHg at 25°C
Melting Point:101-103 °C(lit.)
Refractive Index:-6.5 ° (C=10, Acetone)
Boiling Point:306.4 °C at 760 mmHg
PKA:(1) 3.46, (2) 5.10(at 25℃)
Flash Point:153.4 °C
PSA：94.83000
Density:1.641 g/cm³
LogP:-1.09340

L-(-)-Malic Acid(Cas 97-67-6) Usage

Preparation	L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.
Biochem/physiol Actions	L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
Purification Methods	Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]
Definition	ChEBI: An optically active form of malic acid having (S)-configuration.
General Description	L-Malic acid?is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.

InChI:InChI=1/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1

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97-67-6 Process route

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2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxybutanedioic acid

: 636-61-3,78644-42-5
D-Malic acid

: 97-67-6,78644-42-5
(S)-Malic acid

Conditions

Conditions	Yield
2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxybutanedioic acid; With sodium hydroxide; In water; for 24h; With hydrogenchloride; In water; pH=1.2;

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bromosuccinic acid

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D-Malic acid

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(S)-Malic acid