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CasNo： 33818-15-4
MF： C14H25N4NaO11P2
Appearance： white solid
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Citicoline sodium is white solid, while it's Molecular Formula is C14H25N4NaO11P2. Cytidine-5'-diphosphocholine sodium salt hydrate acts as a neuroprotective agent in situations of hypoxia and ischemia. It is used as biosynthetic intermediate of membrane phospholipids. It is a cerebral vasodilator and inhibits PLA2 activation.
The CAS number of Citicoline sodium is 33818-15-4.
More information of Citicoline sodium 33818-15-4 are:
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Synonyms |
Choline,hydroxide, monoester with cytidine 5'-(trihydrogen pyrophosphate), inner salt,monosodium salt (8CI);Cytidine 5'-(trihydrogen diphosphate),P'-[2-(trimethylammonio)ethyl] ester, hydroxide, inner salt, monosodium salt;Cytidine 5'-(trihydrogen diphosphate), P'-[2-(trimethylammonio)ethyl] ester,inner salt, monosodium salt (9CI);Acticolin;Brassel;Cebroton;Cidifos;Flussorex;Gerolin;IP 302 sodium;Logan;Neurotron;Sinkron; |
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CAS Number |
33818-15-4 |
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Molecular Formula |
C14H25N4NaO11P2 |
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Molecular Weight |
510.31 |
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Melting Point |
259-268°C (dec.) |
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HS CODE |
29349990 |
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PSA |
238.17000 |
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LogP |
-0.14090 |
Citicoline is a nucleic acid derivatives, Geiger found that citicoline can restore brain injury in the animal experiments in 1956. Kennedy study confirmed that citicoline can make brain injury recovery in 1957. Takeda pharmaceutical company in Japan developed and produced it in 1961. It was registered in China in 1988, and is currently the best-selling drug among clinical brain diseases. It plays an important role in the synthesis of lecithin, by promoting the synthesis of lecithin and improving brain function. Experiments show that citicoline can enhance the levels of norepinephrine and dopamine in the central nervous system, thereby it can treat cerebrovascular disease, traumatic brain injury and cognitive impairment caused by various reasons, and there are no obvious side effects.
Articles related to Citicoline sodium:
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Article |
Source |
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Efficient synthesis of cytidine diphosphate choline (CDP-choline) and its analogs |
Sun, Qi,Li, Xiao-Chuan,Gong, Shan-Shan,Sun, Jian,Wang, Cheng-Jun,Wang, Xing-Cong , p. 379 - 387 (2015) |
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Novel application of citicoline pharmaceutical preparation and cerebral infarction acute phase consciousness disorder thereof (by machine translation) |
- Paragraph 0128-0148; 0158-0166, (2020/02/07) |
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