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CasNo: 10309-37-2
MF: C18H24 O
Appearance: white-off solid or colorless liquid
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(S)-Bakuchiol is a meroterpen found in the medicinal resinous shrub Psoralea glandulosa. An analogue of Resveratrol (R150000) with antifungal and anti-tumor effects. Studies have shown that Bakuchiol is a potent cytotoxic agent that exhibiting concentration dependent growth inhibition against leukemia cancer cells.
trans-geranyl bromide
bakuchiol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps
1.1: 3,4,5-trifluoro-N-(2-((S)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6-(((1S,2R,5S)-2-isopropyl-5-methylcyclohexyl)oxy)phenyl)benzenesulfonamide; chromium dichloride; zirconocene dichloride; cesium iodide; nickel dichloride; manganese / tetrahydrofuran / 10 h / -10 °C / Inert atmosphere
2.1: pyridine; methanesulfonyl chloride / 10 h / 20 °C
2.2: 5 h / 20 °C
3.1: methyl magnesium iodide / 0.17 h / 185 °C / Inert atmosphere
With
pyridine; chromium dichloride; manganese; methyl magnesium iodide; zirconocene dichloride; 3,4,5-trifluoro-N-(2-((S)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6-(((1S,2R,5S)-2-isopropyl-5-methylcyclohexyl)oxy)phenyl)benzenesulfonamide; methanesulfonyl chloride; nickel dichloride; cesium iodide;
In
tetrahydrofuran;
|
4-Methoxyphenylacetaldehyde
bakuchiol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps
1.1: 3,4,5-trifluoro-N-(2-((S)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6-(((1S,2R,5S)-2-isopropyl-5-methylcyclohexyl)oxy)phenyl)benzenesulfonamide; chromium dichloride; zirconocene dichloride; cesium iodide; nickel dichloride; manganese / tetrahydrofuran / 10 h / -10 °C / Inert atmosphere
2.1: pyridine; methanesulfonyl chloride / 10 h / 20 °C
2.2: 5 h / 20 °C
3.1: methyl magnesium iodide / 0.17 h / 185 °C / Inert atmosphere
With
pyridine; chromium dichloride; manganese; methyl magnesium iodide; zirconocene dichloride; 3,4,5-trifluoro-N-(2-((S)-4-isopropyl-4,5-dihydrooxazol-2-yl)-6-(((1S,2R,5S)-2-isopropyl-5-methylcyclohexyl)oxy)phenyl)benzenesulfonamide; methanesulfonyl chloride; nickel dichloride; cesium iodide;
In
tetrahydrofuran;
|
The CAS number of 4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL is 10309-37-2.
More information of 4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL 10309-37-2 are:
CAS Number |
10309-37-2 |
Density |
0.963g/cm3 |
Boiling Point |
391.4°Cat760mmHg |
Flash Point |
176.6°C |
Vapor Pressure |
1.1E-06mmHg at 25°C |
Refractive Index |
1.4500 (estimate) |
HS CODE |
2907199090 |
PSA |
20.23000 |
LogP |
5.34410 |
Pka |
10.10±0.26(Predicted) |
Synonyms for 4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL 10309-37-2:Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-;Bakuchiol(7CI);Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-;Phenol,4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]- (9CI);(S)-(+)-Bakuchiol;(S)-Bakuchiol;Drupanol;UP 256;BAKUCHIOL;Backuchiol;
The chemical formula of 4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL is C18H24O which containing 18 Carbon atoms,24 Hydrogen atoms and 1 Oxygen atoms,and the molecular weight of 4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL is 256.388.
Bakuchiol (10309-37-2) is a natural terpenoid antioxidant.It has the follow effects: 1.Inhibits oxidative stress-induced decrease in mitochondrial membrane potential and associated release of pro-apoptotic factors.2.Protects against acute lung injury.3.Displays neuroprotective and anti-inflammatory effects.
InChI:InChI=1/C18H24O/c1-5-18(4,13-6-7-15(2)3)14-12-16-8-10-17(19)11-9-16/h5,7-12,14,19H,1,6,13H2,2-4H3/b14-12+/t18-/m1/s1
Relevant articles related to 4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL:
Article |
Source |
Enantioselective Synthesis of Quaternary Stereocenters via Chromium Catalysis |
Xiong, Yang,Zhang, Guozhu , p. 5094 - 5097 (2016/10/14) |
A facile asymmetric synthesis of Δ3-2-Hydroxybakuchiol, Bakuchiol and ent-Bakuchiol |
Xu, Qian-Qian,Zhao, Qun,Shan, Guang-Sheng,Yang, Xi-Cheng,Shi, Qi-Yuan,Lei, Xinsheng , p. 10739 - 10746 (2013/12/04) |
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